The use of molecular line probe assays for the detection of resistance to second-line anti-tuberculosis drugs: policy guidance
This document provides a summary of the evidence and recommendations for the use of SL-LPA for the detection of mutations associated with resistance to fluoroquinolones and SLID in patients with RR-TB and/or MDR-TB. The objectives of this policy guidance are to assess and compare the diagnostic accuracy ...
Tuberculose Resistente a Múltiplos Medicamentos/diagnóstico, Antibióticos Antituberculose/farmacologia, Técnicas de Sonda Molecular, Testes de Sensibilidade Microbiana, Fluoroquinolonas/uso terapêutico, Farmacorresistência Bacteriana/genética, Genótipo, Mutação, Tuberculose Resistente a Múltiplos Medicamentos/genética, Mycobacterium tuberculosis/efeitos dos fármacos, Mycobacterium tuberculosis/genética