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Resultados: 2

Olaparib for previously treated BRCA mutation-positive hormone-relapsed metastatic prostate cancer

England. National Institute for Health and Care Excellence.
This evaluation uses new cost-effectiveness estimates to update olaparib for previously treated BRCA mutation-positive hormone-relapsed metastatic prostate cancer (NICE technology appraisal guidance TA831). No new clinical evidence was reviewed. Treatments for BRCA mutation-positive hormone-relapsed meta...
Neoplasias da Próstata/tratamento farmacológico, Mutação/efeitos dos fármacos, Proteína BRCA1, Antineoplásicos Hormonais/uso terapêutico
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European Society of Endocrinology Clinical Practice Guidelines on the management of adrenocortical carcinoma in adults, in collaboration with the European Network for the Study of Adrenal Tumors

Fassnacht, M; Dekkers, OM; Else, T; Baudin, E; Berruti, A; de Krijger, R; Haak, HR; Mihai, R; Assie, G; Terzolo, M.
Eur. j. endocrinol; 179 (4), 2018
Adrenocortical carcinoma (ACC) is a rare and in most cases steroid hormone-producing tumor with variable prognosis. The purpose of these guidelines is to provide clinicians with best possible evidence-based recommendations for clinical management of patients with ACC based on the GRADE (Grading of Recomm...
Neoplasias do Córtex Suprarrenal, Metástase Neoplásica, Antineoplásicos Hormonais/uso terapêutico, Etoposídeo/administração & dosagem, Mitotano/uso terapêutico, Doxorrubicina/uso terapêutico, Carcinoma Adrenocortical/diagnóstico, Carcinoma Adrenocortical, Carcinoma Adrenocortical/tratamento farmacológico, Radioterapia, Cisplatino/uso terapêutico, Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico, Ablação por Cateter, Adrenalectomia, Neoplasias do Córtex Suprarrenal/terapia, Carcinoma Adrenocortical/terapia, Quimioembolização Terapêutica
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