This guideline covers identifying and managing familial hypercholesterolaemia (FH), a specific type of high cholesterol that runs in the family, in children, young people and adults. It aims to help identify people at increased risk of coronary heart disease as a result of having FH.
In October 2019, we...
Helsingen, Lise M;
Vandvik, Per Olav;
Jodal, Henriette C;
Agoritsas, Thomas;
Lytvyn, Lyubov;
Anderson, Joseph C;
Auer, Reto;
Murphy, Silje Bjerkelund;
Almadi, Majid Abdulrahman;
Corley, Douglas A;
Quinlan, Casey;
Fuchs, Jonathan M;
McKinnon, Annette;
Qaseem, Amir;
Heen, Anja Fog;
Siemieniuk, Reed A C;
Kalager, Mette;
Usher-Smith, Juliet A;
Lansdorp-Vogelaar, Iris;
Bretthauer, Michael;
Guyatt, Gordon.
Recent 15-year updates of sigmoidoscopy screening trials provide new evidence on the effectiveness of colorectal cancer screening. Prompted by the new evidence, we asked: “Does colorectal cancer screening make an important difference to health outcomes in individuals initiating screening at age 50 to 7...
Kokudo, Norihiro;
Takemura, Nobuyuki;
Hasegawa, Kiyoshi;
Takayama, Tadatoshi;
Kubo, Shoji;
Shimada, Mitsuo;
Nagano, Hiroaki;
Hatano, Etsuro;
Izumi, Namiki;
Kaneko, Shuichi;
Kudo, Masatoshi.
The fourth version of Clinical Practice Guidelines for Hepatocellular Carcinoma was revised by the Japan Society of Hepatology, according to the methodology of evidence-based medicine and partly to the Grading of Recommendations Assessment, Development, and Evaluation system, which was published in Octob...
This guideline covers investigating and managing gastro-oesophageal reflux disease (GORD) and dyspepsia in people aged 18 and over. It aims to improve the treatment of GORD and dyspepsia by making detailed recommendations on Helicobacter pylori eradication, and specifying when to consider laparoscopic fu...
Shroff, Rukshana;
Calder, Francis;
Bakkaloglu, Sevcan;
Nagler, Evi V;
Stuart, Sam;
Stronach, Lynsey;
P. Schmitt, Claus;
H. Heckert, Karl;
Bourquelot, Pierre;
Wagner, Ann-Marie;
Paglialonga, Fabio;
Mitra, Sandip;
Stefanidis, Constantinos J.
There are three principle forms of vascular access available for the treatment of children with end stage kidney
disease (ESKD) by haemodialysis: tunnelled catheters placed in a central vein (central venous lines, CVLs), arteriovenous fistulas (AVF), and arteriovenous grafts (AVG) using prosthetic orbiol...
This guideline covers care for women of any age (including girls and young women under 18) who request an abortion. It aims to improve the organisation of services and make them easier for women to access. Detailed recommendations on conducting abortions at different gestational stages are also included,...
This guideline covers recognising, diagnosing and managing attention deficit hyperactivity disorder
(ADHD) in children, young people and adults. It aims to improve recognition and diagnosis, as well
as the quality of care and support for people with ADHD.
In September 2019 we amended the recommendation o...
This guideline covers preventing, identifying and managing latent and active tuberculosis (TB) in children, young people and adults. It aims to improve ways of finding people who have TB in the community and recommends that everyone under 65 with latent TB should be treated. It describes how TB services ...
For patients with acute respiratory insufficiency, mechanical ("invasive") ventilation is a fundamental therapeutic measure to ensure sufficient gas exchange. Despite decades of strong research efforts, central questions on mechanical ventilation therapy are still answered incompletely. Therefore, many d...
Hypertension is the most common disease in the world, affecting more than a billion people, and the leading cause of death and disability (Williams 2018).
In Estonia as well, cardiovascular diseases, including hypertension with complications, rank first among the causes of morbidity and death. High bloo...