El objetivo principal de esta Guía es recoger recomendaciones para el diagnóstico y el tratamiento de mujeres con cáncer de mama metastásico....
Neoplasias da Mama/diagnóstico,
Neoplasias da Mama/terapia,
Metástase Neoplásica,
Trastuzumab/uso terapêutico,
Tamoxifeno/uso terapêutico,
Gosserrelina/uso terapêutico,
Inibidores da Aromatase/uso terapêutico,
Everolimo/uso terapêutico,
Tomografia por Emissão de Pósitrons/métodos,
Tomografia por Emissão de Pósitrons combinada à Tomografia Computadorizada/métodos,
Neoplasias Ósseas/secundário,
Biópsia,
Abordagem GRADE,
Antineoplásicos/administração & dosagem
El objetivo principal de la guía es proporcionar a los profesionales sanitarios, recomendaciones para la prevención, el diagnóstico y el manejo terapéutico de los pacientes con Linfoma B Difuso de célula grande (LBDCG), que presentan (o tienen riesgo de) afectación leptomeníngea o del parénquima ...
Linfoma Difuso de Grandes Células B/tratamento farmacológico,
Linfoma Difuso de Grandes Células B/diagnóstico,
Doenças do Sistema Nervoso Central/etiologia,
Punção Espinal/métodos,
Biópsia/métodos,
Espectroscopia de Ressonância Magnética/métodos,
Metotrexato/uso terapêutico,
Rituximab/uso terapêutico,
Antineoplásicos/uso terapêutico,
Abordagem GRADE,
Doenças do Sistema Nervoso Central/prevenção & controle
Tests based on the detection of mycobacterial lipoarabinomannan (LAM) antigen in urine have
emerged as potential point-of-care tests for tuberculosis (TB). LAM antigen is a lipopolysaccharide
present in mycobacterial cell walls, which is released from metabolically active or degenerating
bacterial cells ...
The Consolidated guidelines on HIV testing services bring together existing guidance relevant to the provision of HIV testing services (HTS) and addresses issues and elements for effective delivery of HTS that are common in a variety of settings, contexts and diverse populations. In addition, this docume...
Early detection of tuberculosis (TB) is essential to improve health outcomes for people with TB, and to reduce TB transmission more effectively. Systematic screening in high risk groups is a complement to efforts to improve the patient-initiated pathway to TB diagnosis (that is, diagnosing TB among peopl...
In 2011 WHO conditionally recommended the use of at least 36 months of isoniazid preventive therapy (IPT) (as a proxy for lifelong or continuous treatment) for people living with HIV in high TB-prevalence and transmission settings. The evidence of the benefits and harms of 36-month IPT compared to 6-mont...
In 2015 WHO updated the mhGAP guidelines, first issued in 2009, for the management of mental, neurological and substance use (MNS) disorders. In order to reduce the gap and to enhance the capacity of Member States to respond to the growing challenge, the World Health Organization (WHO) developed the Ment...
This early-release guideline makes available two key recommendations that were developed during the revision process in 2015. First, antiretroviral therapy (ART) should be initiated in everyone living with HIV at any CD4 cell count. Second, the use of daily oral pre-exposure prophylaxis (PrEP) is recomme...
The primary audience for this guideline includes health-care professionals who are responsible for developing national and local health-care protocols and policies, as well as managers of maternal and child health programmes and policy-makers in all settings. The guideline will also be useful to those di...
Meningococcal meningitis is a bacterial form of meningitis, a serious infection of the meninges (brain membrane). It can cause severe brain damage and is fatal in 50% of cases if untreated. It provides a concise overview of the World Health Organization (WHO) strategy to detect and respond to meningitis ...
