BIGG

The use of lateral flow urine lipoarabinomannan assay (‎LF-LAM)‎ for the diagnosis and screening of active tuberculosis in people living with HIV: policy guidance

Ano de publicação: 2015

Tests based on the detection of mycobacterial lipoarabinomannan (LAM) antigen in urine have emerged as potential point-of-care tests for tuberculosis (TB). LAM antigen is a lipopolysaccharide present in mycobacterial cell walls, which is released from metabolically active or degenerating bacterial cells and appears to be present only in people with active TB disease. Urine-based testing would have advantages over sputum-based testing because urine is easy to collect and store, and lacks the infection control risks associated with sputum collection.