Ebola and Marburg disease outbreaks remain important public health threats. The newly published WHO Infection prevention and control guideline for Ebola and Marburg disease contains the Organization's most up to date recommendations for IPC measures to be implemented in all health facilities when caring for people with, or managing outbreaks of, Ebola or Marburg disease. This comprehensive guideline is based on GRADE methodology and uses the best available evidence to ensure patients with Ebola or Marburg disease can be safely cared for while preventing transmission within health facilities and promoting health and care worker safety. This guideline includes 11 new recommendations and 10 new good practice statements. 9 recommendations from previously published IPC documents have been carried forward and are included in this new document. This guideline replaces three previously published IPC guidance/guidelines from 2014 and 2016.