A clinical summary of this KDP was published in the Journal of the Ministry of Health of the Czech Republic . Sarcomas are malignant tumors of connective tissues. It is a heterogeneous group of tumors given by a wide spectrum of histotypes with different biological behavior and diverse anatomical localization. As such, sarcomas account for less than 1% of all malignant tumors in adults and about 15% of malignancies in childhood. Soft tissue sarcomas are among the rare tumors that are still on the fringes of general interest. However, patients who develop sarcoma perceive them differently. The basis of the successful treatment of most of them is a quality diagnosis, and above all a well-planned and surgical treatment performed by an erudite operator, in workplaces where this diagnosis is not uncommon.

This clinical guideline focuses on 11 areas:

Diagnostics Therapy of localized, locally operable soft tissue and visceral sarcomas Therapy of localized, locally inoperable soft tissue and visceral sarcomas Therapy of advanced/generalized, locally operable soft tissue and visceral sarcomas Therapy of advanced/generalized, locally inoperable soft tissue and visceral sarcomas Therapy of recurrent, locally operable soft tissue and visceral sarcomas Therapy of retroperitoneal sarcomas GIST therapy Therapy of "childhood" sarcomas Desmoid therapy (aggressive fibromatosis) Follow-up care/dispensary.