In 2019, the Executive Guideline Steering Group (GSG) for the World Health Organization (WHO) maternal and perinatal health recommendations prioritized updating the then current WHO recommendations on antiplatelet agents for the prevention of pre-eclampsia. This decision was based on new evidence on the subject that had become available. The recommendation in this document thus supersedes the previous WHO recommendations on antiplatelet agents for the prevention of pre-eclampsia as published in the 2011 guidelines, WHO recommendations for the prevention and treatment of pre-eclampsia and eclampsia