Postpartum haemorrhage (PPH) is commonly defined as a blood loss of 500 ml or more within 24 hours after birth, and affects about 5% of all women giving birth around the world. The primary aim of these recommendations is to improve the quality of care and outcomes for women giving birth, as they relate to PPH and its complications. These recommendations thus provide a foundation for sustainable implementation of routine uterotonic use in the immediate postpartum period globally.